PRKAA1 and diabetes mellitus: In Fig. 3A, B, Western blot analysis revealed that Cai’s Herbal Tea induced higher expression of the ratio of LC3 II/LC3 I, P-ACC/ACC, P-AMPK/AMPK whereas the lower expression of the ratio of P-mTOR/mTOR, P62 of the pancreas islet in DM mice than control mice in a dose-dependent way(P < 0.01).