We documented up-regulation in the expression of IFN-γ, IL12p70, IL-18, IL-20, MIF, TNF-α, TSLP, BLC, Eotaxin-1, Eotaxin-2, IP-10, MIP-1a, MIP-3a, FGF-2, MMP-1, TNFRII and TWEAK, which are implicated in the modulation of inflammation, apoptosis, tumor growth, invasion, and angiogenesis. The gene discussed is TNFSF12; the disease is neoplasm.