Multiple types of cells were found within the tumor organoid in a heterogeneous manner, such as paneth cells expressing Lysozyme (Lysz) and epithelial cells expressing Villin 1 (Vill), while a lower abundance of Mucin2 (Muc2)-expressing goblet cells were observed in the tumor organoids (Fig. 1C). The gene discussed is VIL1; the disease is neoplasm.