ACOX1 and hepatocellular carcinoma: Furthermore, adipose triglyceride lipase (ATGL) was found to be highly expressed in human HCC tissues, while FA-related oxidases such as carnitine palmitoyl transferase 1A (CPT1A) and acyl-coenzyme A oxidase 1 (ACOX1) were found to be downregulated, leading to increased breakdown of stored lipids in HCC cells and elevated levels of diglycerides (DAG) and free FA (FFA) [30, 31].