Therefore, we investigated the expression of PD-L1, ICAM-1, CXCL10, and IFNs-mediated ISG15 expression in patients with lung cancer (LUAD), liver cancer (LIHC), and colorectal cancer (COAD) using the available GEPIA based on the TCGA database. This evidence concerns the gene CXCL10 and colorectal cancer.