CYP3A4 and steatosis: CYPRO, a fungicide shown to induce steatosis in rodents (al-Eryani et al. 2015; Marx-Stoelting et al. 2017), decreased gene expression of CYP7A1, CYP27A1, BAAT, CYP3A4, ACAT2, ABCB11, ABCA1, SCARB1, HNF4A, PXR, ANXA10, while it upregulated CCL20 gene expression.