The single non-Vδ1Vδ2 cluster present in the tumours had a high expression of CD45RO and Fas (CD95), and also a higher expression than most other clusters of several proteins expressed in activated cells, such as ICOS (CD254), OX-40 (CD134), CD25, and FoxP3 (Fig. 5E). The gene discussed is ICOS; the disease is neoplasm.