What's more, the enrichment of effector T cells in CMT93 tumors was employed to further understand the role of tumor infiltrating cytotoxic T cells, and an increased percentage of IFNγ+CD8+, GZMB+CD8+ and TNFα+CD8+ T cells, which represent the activated and cytotoxicity of CD8+ T cells, were found in SRC‐1‐deficient tumors (Figure 2D). The gene discussed is TNF; the disease is neoplasm.