The growth and size of SRC‐1‐deficient tumors were significantly attenuated in both nude mice and immunocompetent mice compared to Ctrl tumors (Figure 1D,F), but the normalized weight of SRC‐1‐deficient tumors in immunocompetent mice was lower than that in nude mice (Figure 1E,G), suggesting that immune system in immunocompetent mice may contribute more to inhibit tumor growth after SRC‐1 down‐regulation in tumor. The gene discussed is NCOA1; the disease is neoplasm.