Several studies have demonstrated that SRC‐1 is highly expressed in multiple types of human solid cancers and plays a vital role in cancer cell initiation, progression, and metastasis by modulating different signaling pathways.[24, 25] In addition, PD‐L1 is overexpressed in tumor cells, and binds to PD‐1 to inhibit the activation of immune cells, thereby mediating tumor immune escape. This evidence concerns the gene NCOA1 and cancer.