TNF and autoimmune polyendocrinopathy: The effect of APS on the serum levels of EPO, G-CSF, IL-3, and TNF-α cytokines in the model mice illustrated in Figure 8, show significantly lower levels of EPO, G-CSF, and IL-3 (p < 0.01) and significantly higher level of TNF-α (p < 0.01) in mice in the MOD than in the NC group.