ATG7 and autoimmune thrombocytopenic purpura: Notably, Sun et al. reported that megakaryocyte dysfunction in ITP is associated with abnormal autophagy, which could be due to the deletion of autophagy-related genes, such as ATG7, and the overactivation of mTOR-related signaling pathways (Sun and Shan, 2019), which is highly relevant to the results of our study.