One with ankylosing spondylitis had an ESR =34 mm/h (normal range <20mm/h) and CPR=0.9 mg/dL (normal range <0.5 mg/dl), and the patient with an antiphospholipid syndrome had an ESR=21 mm/h, CPR=0.7 mg/dL and SAA=8 mg/dL (normal range <7 mg/dL). The gene discussed is SAA1; the disease is antiphospholipid syndrome.