CKMT2 and rectum adenocarcinoma: To evaluate the mechanism underlying the regulation of the Warburg effect by CKMT2, we analyzed the correlation between CKMT2 and glycolysis-related gene expression in colon adenocarcinoma and rectum adenocarcinoma from the Gene Expression Profiling Interactive Analysis (GEPIA) database (http://gepia.cancer-pku.cn/index.html) (Figs. 5A–5M).