Given evidence that there is a beneficial effect of DGLA on the level of brain-derived neurotrophic factor (BDNF) which can interact with inflammation as the risk factor in the cardiovascular disorders (56), including stroke, the relatively stable DGLA level in the FO piglets might be beneficial for piglets to survive epically when they were facing the increased body temperature under LPS challenge. The gene discussed is BDNF; the disease is cardiovascular disorder.