[181] developed N-benzyl-N-methyl-2-[7,8-dihydro-7-(2-[18F]fluoroethyl)-8-oxo-2-phenyl-9H-purin-9-yl]acetamide ([18F]FEDAC), which is a radioprobe specific for TSPO expressed by macrophages and aHSCs, for the noninvasive visualization of liver fibrosis in vivo using PET. This evidence concerns the gene TSPO and Hepatic fibrosis.