There are several polymorphisms of BRCA1 and BRCA2 associated with increased risk of sex-specific cancers such as breast cancer (Valentini et al., 2024), ovarian cancer (Risch et al., 2001; Horackova et al., 2023), and endometrial cancer (Sorouri et al., 2023)in women and prostate cancer in men (Kalampokis et al., 2024). The gene discussed is BRCA1; the disease is breast carcinoma.