Initially, genes associatedwith clubfoot (PITX1, TBX4, HOXA9, HOXD10, HOXD12,HOXD13, HOXA9, TPM1, TPM2, COL9A1, FLNB, CASP8,CASP10, UTX, CHD1, RIPPLY2, CAND2, WNT7) werescreened for potential variants. This evidence concerns the gene KDM6A and clubfoot.