Initially, genes associatedwith clubfoot (PITX1, TBX4, HOXA9, HOXD10, HOXD12,HOXD13, HOXA9, TPM1, TPM2, COL9A1, FLNB, CASP8,CASP10, UTX, CHD1, RIPPLY2, CAND2, WNT7) werescreened for potential variants. This evidence concerns the gene CAND2 and clubfoot.