AKT1 and cancer: The PI3K/AKT and MAPK/ERK signaling pathways stand out as essential signaling pathways across various types of cancer (He et al., 2021; Moon and Ro, 2021), with particular significance as key contributors in chemoresistance and survival of TNBC (Bartholomeusz et al., 2012; Costa et al., 2018; Nedeljković and Damjanović, 2019).