CREB3 and hepatocellular carcinoma: Western blotting and qRT‐PCR analysis showed that CREB3 was highly expressed in HCC cell lines with low invasiveness, including Hep3B, PLC/PRF/5, Huh7, and was relatively less expressed in cell lines with high invasiveness including HLF, MHCC‐97H (97H), and HCC‐LM3 (LM3)21, 22 (Figure 1B,C).