CTNNB1 and gastric cancer: (53) found that the expression of myosin heavy chain 9 (MYH9) was increased in metastatic gastric cancers and was correlated with a poor prognosis; MYH9 provides gastric cancer cells with the ability to resist apoptosis and promote metastasis by inducing the transcription of CTNNB1.The expression of the destruction complex member APC is downregulated in GC, leading to lymph node metastasis and distant metastasis of GC (54).