The connection between EphA3/PD-L1 co-expression and overall PD-L1 expression is intricately linked to a CD8 T effector cell signature in urothelial carcinoma tissues, as unveiled through gene expression analyses (31).To delve deeper into the significance of EphA3 in KIRP, an exploration was undertaken using the TIMER databases to uncover its correlations with B cells, CD8+ T cells, CD4+ T cells, and neutrophil infiltration. The gene discussed is CD274; the disease is urothelial carcinoma.