This is similar to available local data where 53 (53.5%) were GAD-65 positive and 16 (16.2%) were IA2 positive.7 one international studies also supports same findings where anti-GAD and anti-IA2 auto-antibodies were found in 76.92% and 62.82% respectively in a mix group of newly and established diabetic children.16 Hence, these two antibodies can detect patients early and can persist several years after diagnosis of T1D. This evidence concerns the gene PTPRN and type 1 diabetes mellitus.