There are two recent studies discussing that the existence of anti-Glutamic Acid Decarboxylase (anti GAD) with various islet cell antibodies in children is concomitant with leisure advancement of Type-1 diabetes.8 Being the largest in province, we get referrals from different regions of the country, hence this study will help us more to understand the autoimmunity pattern of Pakistani children in developing diabetes. The gene discussed is GAD1; the disease is diabetes mellitus.