Protein western blotting proved that CA could reverse the low expression of CPT1A and high expression of SREBP1c in renal tissue of DKD mice, which was consistent with the results in vitro, and further verified our conclusion that CA could improve renal fibrosis by reducing renal lipid accumulation in DKD mice (Figure 5(D–F)). The gene discussed is SREBF1; the disease is renal fibrosis.