CD274 and neoplasm: Experimental data revealed that compared to anti‐PDL1 antibodies group and ΔECHy group, anti‐PD‐L1 antibodies combination treatment with ΔECHy did retard tumor growth rate and showed a significant promotion in survival, suggesting that remodeling tumor stroma can effectively promote therapeutic drug immune checkpoints and subsequent immune cell infiltration to improve the efficacy of tumor immunotherapy.