Conversely, in the tumor tissues derived from mice implanted with LLC‐PRPS2 cells, we observed a significant decrease in the percentage of CD4+ T cells (Figure 4a) and CD8+ T cells (Figure 4b), coupled with a significant increase in the percentage of TAMs (Figure 4c), M‐MDSC (Figure 4d), and PMN‐MDSC (Figure 4e). Here, CD8A is linked to neoplasm.