CD4 and neoplasm: Additionally, in the tumor tissues of mice implanted with LLC‐PRPS2‐shCCL2 cells, we observed a significant increase in the percentage of CD4+ T cells (Figure 5g) and CD8+ T cells (Figure 5h), accompanied by a significant decrease in the percentage of TAMs (Figure 5i), M‐MDSC (Figure 5j), and PMN‐MDSC (Figure 5k).