SIRPA is an immunoglobulin-like cell surface receptor for CD47 (a cell surface protein that is involved in the promotion/regulation of cellular proliferation) and has been associated with a range of infectious diseases, including Theileria annulata infection in cattle44 (T. annulata is the causative agent of tropical theileriosis across North Africa and Asia, and is closely related to Theileria parva found in Eastern Africa). This evidence concerns the gene SIRPA and infectious disease.