ATP1A3 and myocardial infarction: To define the potential working mechanism of PEX3 on promoting myocardial repair, we isolated the myocardial plasma membrane proteins of adult mice following myocardial infarction in Pex3-KO mice and WT mice at P56, and identified them by subcellular markers (cell membrane marker-ATP1A3, cytoplasmic maker-GAPDH, and nuclear marker-HH3) to detect differentially expressed proteins at the cell membrane by proteomics (Supplemental Fig. 10a, Fig. 7a).