YTHDC1 and colon adenocarcinoma: To further explore this relationship between YTHDC1 and TP53 that we observed in the A549 lung carcinoma cell line in other tumour types, we conducted a correlation analysis for differential gene expression in different tumours from TCGA database, including lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC) and colorectal adenocarcinoma (COAD) patients.