To further explore this relationship between YTHDC1 and TP53 that we observed in the A549 lung carcinoma cell line in other tumour types, we conducted a correlation analysis for differential gene expression in different tumours from TCGA database, including lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC) and colorectal adenocarcinoma (COAD) patients. The gene discussed is YTHDC1; the disease is lung carcinoma.