METTL2B and neoplasm: Interestingly, even considering the inherent heterogenicity between patient samples, the top three candidates from the p53-enhanced-response population (ASH2L, MEPCE and METTL2B), showed a clustered positive Pearson correlation with p53 alteration score, indicating that the higher the expression of these genes in the tumour, the more altered the p53 response.