TNFAIP6 and Intervertebral disk degeneration: TSG6 is an inflammatory factor with suggestive therapeutic effects in corneal wounds, myocardial infarction, injured central nervous system, chronic liver damage, and intervertebral disc degeneration (Zhang et al, 2013; Lee et al, 2015; Lee et al, 2009; Wang et al, 2017; Yang et al, 2018b).