We used the keywords ‘type 2 diabetes’, ‘diabetes technology’, ‘continuous glucose monitoring’, ‘flash glucose monitoring’, ‘intermittently-scanned continuous glucose monitoring’, ‘real-time continuous glucose monitoring’, ‘continuous subcutaneous insulin infusion’, ‘insulin pump’, ‘closed-loop’, ‘automated insulin delivery’, ‘artificial pancreas’, ‘connected insulin devices’, ‘smart insulin pen’ and ‘smart insulin pen caps’ alone and in combination to retrieve available literature from PubMed from inception until January 2024. This evidence concerns the gene INS and diabetes mellitus.