Hypocellularity was observed in all major T cell subpopulations, with an absolute cell count normalized to the control of 56.78 ± 12.67%, 55.17 ± 12.59% and 70.68 ± 15.95% for CD8+, helper (CD4+ FOXP3−) and regulatory (CD4+ FOXP3+) T cells, respectively, on day 4 after tumor IR (Fig. 7C). This evidence concerns the gene CD4 and neoplasm.