In addition to TRMT10A, mutations in various tRNA modification enzyme genes (TRMT5, NSUN2, NSUN3, WDR4, PUS3, PUS7, CTU2, YRDC, OSGEP, TP53RK, TPRKB, LAGE3, MTO1, GTPBP3, THG1L, and TRIT1) cause short stature (5), and all of these mutations are associated with brain disorders. This evidence concerns the gene PUS7 and brain disorder.