RNA-Seq expression for HSPD1 (gene name for HSP60) within synovial tissue was compared between the lympho-myeloid, diffuse-myeloid, and pauci-immune fibroid histological groups in patients with early or established RA using bulk RNA-Seq data generated by us from synovial biopsies obtained as part of the Pathobiology of Early Arthritis Cohort (PEAC) study and the R4RA randomized clinical trial (26–28). The gene discussed is HSPD1; the disease is arthritic joint disease.