Cluster 3, which identified genes upregulated at day 7 post-infection, was highly enriched for T cell responsive genes, including those involved in T cell activation, lymphocyte proliferation, and TCR signaling, e.g. CD3D/E/G, CD8A/B, CD28, CD40LG, and GATA3 (Fig 3C). This evidence concerns the gene CD40LG and infection.