We saw no significant difference between Tg and HbTg groups in these parameters at day 5 (Fig 6A–6E and S1 Table) post Tg infection, prior to the start of mortality (Fig 1B), however inflammation score (Fig 6A) and Il-22 (Fig 6E) of most animals with HbTg infection were similar to Hb mice compared to Tg alone. The gene discussed is IL22; the disease is infection.