Different lymphocytes produce IFN© within this immune organ, including NK and CD8+ T cells, traditionally associated with IFN© production during Tg infection [16, 17, 60, 61], as well as NKT, ©δ and CD4+ T cell more recently implicated in the inflammatory response to Tg infection [22, 62, 63]. The gene discussed is CD8A; the disease is infection.