SH2D3A and Alzheimer disease: This is further supported by the observation that the SARS CoV‐2–encoded NSP1 protein, which blocks general translation initiation through binding to the PIC complex [100], prevents the symptoms of AD, PD, and ALS, which are associated with accumulation of protein aggregates due to ribosome stalling, but not other neurodegenerative disorders that are not known to be associated with ribosome stalling [101].