CXCL10 and coinfection: To statistically test whether viral coinfections increased the CXCL10 response, we used multiple linear regression analysis to predict CXCL10 in single infections vs. coinfections, using SARS-CoV-2 load (40-Ct) as a continuous predictor variable and the presence of any viral coinfection as a binary predictor variable (0 = no viral coinfection; 1 = viral coinfection) (Fig. S2 A).