The univariate Cox analysis was also applied to identify 11 prognostic TRP‐related genes specific to gliomas, including TIMP1, SERPINE1, NNMT, IGFBP2, EMP3, COL4A2, COL4A1, COL3A1, COL1A2, ANXA1, and CHI3L1 (Figure 6B). This evidence concerns the gene SERPINE1 and central nervous system cancer.