We found that all genes from the TIS were statistically significant between the Ehmt2fl/fl pancreas compared to the Ehmt2+/+ controls during acute pancreatitis, with a range from 0.34 for Psmb10 as the least log2 FC to 3.48 for Tigit with the most significant change (Table 6). Here, EHMT2 is linked to acute pancreatitis.