For instance, upregulated DEGs in both the Pdx1-Ehmt2fl/fl and P48-Ehmt2fl/fl acute pancreatitis groups, that were classified within the inflammatory response and immune signaling functional group, were enriched in pathways such as TNFα signaling via NF-kB, interferon gamma response, allograft rejection, IL-6/JAK/STAT3, and IL-2/STAT5 signaling. The gene discussed is TNF; the disease is acute pancreatitis.