PDX1 and acute pancreatitis: Moreover, we performed MCP Counter deconvolution to evaluate the immune cell infiltrate of the P48-Ehmt2+/+ and P48-Ehmt2fl/fl animals with acute pancreatitis (Supplementary Figure S3A), finding similar changes with Ehmt2 knockout as the Pdx1-Cre acute pancreatitis model (Figure 3A), namely, an increase in markers for macrophages, T-cells, and neutrophils.