Among biomarkers, CgA (HR = 7.1; P = 0.0001), ALP (HR = 4.9; P = 0.2), number of prior systemic treatment divided by time from diagnosis (HR = 1.2; P = 0.1) and primary tumor site (HR = 1.3; P = 0.007) were significant predictive features. Here, CGA is linked to neoplasm.