As expected, ALDH1A2 was significantly overexpressed in the MPS-I NB group (Figure 4 G and Figure S6) and was not only identified as a hazardous factor by univariate Cox regression (HR: 1.26, 95%CI: 1.15‐1.38, p < 0.001; Table S9), but also negatively correlated with the overall survival time of patients with NB (Figure 4 H and I). This evidence concerns the gene ALDH1A2 and neuroblastoma.