MKI67 and neoplasm: The antiproliferative activity of AZD7762 and etoposide was re-verified with immunofluorescence staining, which showed that the percentage of proliferative tumor cells (Ki67+) was significantly reduced in the AZD7762-treated MPS-I (0.12 ± 0.03) and etoposide-treated MPS-II (0.07 ± 0.02) groups compared to the other groups (Figure 10 D and E).