STAT3 and acute myeloid leukemia: Higher levels of LINC00265 were also found in the serum of patients with acute myeloid leukemia (AML), which is correlated with lower overall survival rate because LINC00265 contributes to migration and invasion of tumor cells by regulating PI3K/AKT and signal transducer and activator of transcription 3 (STAT3) signaling [12–14].