<h4>Objective</h4>This study aimed to investigate the role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in triple-negative breast cancer (TNBC).<h4>Methods</h4>ROR2 expression in primary TNBC and metastatic TNBC tissues was analyzed by immunohistochemical staining and PCR. The gene discussed is ROR2; the disease is triple-negative breast carcinoma.