The results indicate that the main factors influencing mortality in sepsis include gender, age, mode of admission, treatment upon admission, use of emergency mechanical ventilation, septic shock, administration of vasoactive drugs, heart rate, respiratory rate, SpO2, oxygen supplementation, PaO2/PAO2 ratio, A-aDO2, OI, PLT, SCr, BUN, D2 dimer, CRP, PCT, IL-6, ICU hospitalization, total length of hospital stay, ICU/total hospital stay, NEWS score, GCS score, SOFA score, SOFA-L score, NEWS-L score, and lactate level. This evidence concerns the gene IL6 and septic shock.