Compared with group C, in the MND group, the levels of IL-6 (129.075±16.662 vs 26.137±5.281, p<0.001), TNF-α (81.200±13.492 vs. 10.237±1.571, p<0.001), and IL-1β (107.950±23.918 vs. 22.387±5.464, p<0.001) were significantly higher. The gene discussed is IL1B; the disease is mild neurocognitive disorder.