Subsequently, we adoptively transferred bone marrow cells from <i>Il17ra</i> <sup>ΔTreg</sup> mice to a mouse model of sporadic colorectal cancer (<i>Cdx2-Cre</i> <sup>+</sup>/<i>Apc</i> <sup>F/+</sup>), to selectively ablate IL-17 direct signaling on Tregs in colorectal cancer. Here, APC is linked to colorectal cancer.