In our ongoing studies on HL, we identified an individual homozygous for an FGF3 variant (c.493A > G; p.Arg165Gly) and another individual who is heterozygous for a GREB1L variant (c.556T > C; p.Cys186Arg) (Fig. 1a–b and Supplementary Table S3). This evidence concerns the gene FGF3 and Hodgkins lymphoma.