Integrations of clinical genomics, pathology and FISH have revealed that EWSR1-fusions with the CREB family member ATF1 (EWSR1-ATF1) are also drivers in malignant mesothelioma (MM), in addition to CCS (Table 1; Figure 3) (Desmeules et al., 2017). Here, EWSR1 is linked to Miyoshi myopathy.