The transdifferentiation of HSC from quiescent, vitamin A‐storing cells to proliferating, fibroblastic myofibroblasts and the secretion of α‐SMA, Col1a1, and Col3a1 are stimulated by various injuries; cytokines with pro‐fibrotic properties such as TGF‐β1 are now recognized as major drivers of liver fibrosis. Here, COL1A1 is linked to Hepatic fibrosis.