AR and posterior cortical atrophy: Ferroptosis, a recently identified form of programmed cell death, is characterized by the accumulation of iron‐dependent lethal lipid hydroperoxide (LPO), including reactive oxygen species (ROS) and polyunsaturated fatty acids (PUFAs).[7] Iron ions (Fe2+/Fe3+) can react with peroxides in cells and generate ROS through the Fenton reaction.[8] AR inhibitors can reprogram the metabolic state of PCa, leading to an accumulation of lipids, which supply energy for bioenergetic processes and cell proliferation.