Furthermore, glycosylated B7-H4 inhibits eukaryotic translation initiation factor 2 subunit alpha (eIF2a) phosphorylation, thereby interrupting the exposure of cells to calreticulin (CALR) and the heat shock proteins, including heat shock protein 70 (HSP70) and heat shock protein 90 (HSP90), and suppressing cancer cell immunogenicity[83]. This evidence concerns the gene CALR and cancer.